Prescription Medication Use and Antinuclear Antibodies

SSS senior statistician Gregg Dinse (first author) and researcher Caroll Co are authors of an article in the Journal of Autoimmunity that describes an examination of data from the 1999–2004 National Health and Nutrition Examination Surveys to investigate possible links between specific prescription medications and the presence of antinuclear antibodies (ANA), which are of interest because they can sometimes indicate an autoimmune disease. The researchers found no evidence that most medications previously associated with ANA in specific individuals were risk factors for ANA in the general population, though they found novel positive ANA associations with several other medications and unexplained inverse ANA associations with certain classes of medications. Other authors of the article include researchers from the National Institute of Environmental Health Sciences, University of Wisconsin-Milwaukee, University of Florida Health Science Center, University of Rochester School of Medicine and Dentistry, and Icahn School of Medicine at Mount Sinai.

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