Exogenous Estrogen Exposure Responses in Infants Fed Soy Formula

SSS health researcher Kerry James is among the authors of an article in the Journal of Clinical Endocrinology and Metabolism that describes a comparison of estrogen-responsive postnatal development in infants fed exclusively soy formula, cow-milk formula, or breast milk. Infants fed soy-based formula are highly exposed to isoflavones—chemicals with hormone-like activity. Relative to girls fed cow-milk formula, those fed soy formula had characteristics consistent with response to exogenous estrogen exposure, and the authors concluded that further evaluation of the effects of soy on child development is needed. The authors of the article included researchers from the National Institute of Environmental Health Sciences, Vanderbilt University Medical Center, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, the Centers for Disease Control and Prevention, LabCorp, and Quest Diagnostics Nichols Institute.

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